Guinea Pig Cushings Disease

Guinea Pig Cushings Disease

What is Guinea Pig Cushings Disease?

Although normally uncommon in Guinea Pigs, Cushing’s Disease occurs when the Adrenal Gland produces too much of the hormones that control Stress, Blood Pressure and Heart Rate. Fluctuations in hormone levels may lead to many problems such as :-

  • Hair Loss
  • High Blood Pressure
  • And increased Urination

Increasing risk of diabetes. Managing the disease is the only solution to date, and treatments are available to help reduce the symptoms and allow your Guinea Pig to live a happy and relatively comfortable life.


Cushing’s Disease often develops in response when benign tumours located in the pituitary or adrenal glands located near the kidneys. While the tumours are not often removed due to the high risk of surgery, drugs are available to stabilise hormone production and alleviate symptoms.


Symptoms of Cushing’s Disease can vary from Guinea Pig to Guinea Pig. However the common Symptoms are :-

  • Mild Discomfort of Hair Loss
  • Increased Thirst
  • Rapid Breathing ^
  • Skin Lumps ^

^ These symptoms being the more serious conditions.


Cushing’s Disease may be diagnosed through the use of an Ultrasound. An Ultrasound shows the size of the Adrenal Gland. Adrenal Glands in a Healthy Guinea Pig should be around 3mm to 4mm in size, an enlargement of these may indicate the disease, or even detecting a tumour of one or both glands.


It is recommend that Veterinarians Ultrasound a Healthy Guinea Pig alongside the Guinea Pig with the medical problem for comparison, this is the easiest way to recognise differences and problems.


Cushing’s Disease is not an infectious disease which can be passed from Guinea Pig to Guinea Pig or Guinea Pig to Human as it is an hormonal imbalance.

Treatment’s Available For Cushing’s Disease

Daily treatments of L-Deprenyl helps reduce the size of the Adrenal Gland, while other drug therapy may be used to destroy part of the glands to decrease the overproduction of hormones.

Herbal treatments such as Cushex drops help relax the Adrenal Glands to decrease the overproduction of hormones.

Partnering with your Veterinarian to decide which treatment option is best for your Guinea Pig’s health is paramount !

These Treatments are dangerous and NEED to be monitored carefully by a Veterinarian to prevent damage to the glands